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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence in accordance with a news release by them on 10-12-2010.

Using two separate drugs to shed pounds can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you need to err to the side of caution and allow the FDA do its job and demand some research be done so the public understands the side effects and dangers of the medications before we drive them. Keep in mind that drug companies will be in business to make money and that they would say everything to keep people on the medications.

Researchers found out that participants using this drug to get a year, dropped a few pounds within four weeks and have kept the weight off through the entire 56 weeks with the study. Contrave is often a combination from the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs which can be made up of many active ingredient, that might make them more effective and safer.

Combo-pilling could be the newest fad or better yet the newest to come under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular is the fact that as of right now there are no long term prescription slimming capsules that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures really are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug could also raise blood pressure levels and heart rate, and must not be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must not used in patients with uncontrolled high hypertension, along with by a person with heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients for the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.

"This will be the first drug I'm alert to that targets both appetite and reward centres inside the brain," he explained.