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Researchers discovered that participants investing in this drug to get a year, dropped a few pounds within one month and have kept the load off throughout the 56 weeks of the study. Contrave can be a combination of the drugs naltrexone and bupropion, which usually reflect a fresh trend of weight-loss drugs which are made up of several active ingredient, which might make them more efficient and safer.
Combo-pilling could be the newest fad or in addition to this the newest to come under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills has become popular will be the fact that since right now there aren't any long term prescription weight loss supplements that have been licensed by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be approved by the FDA.
Seizures are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug could also raise hypertension and pulse rate, and mustn't be used in individuals with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.
The FDA also warned that Contrave can raise hypertension and heartrate and must not used in patients with uncontrolled high blood pressure level, as well as by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients which has a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients towards the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.
"There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.