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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight-loss in addition to a reduced-calorie diet and exercising.

Using two separate drugs to lose weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with fat loss and the those who go through it you need to err assisting caution and let the FDA do its job and demand some investigation be done so the public knows the side effects and hazards of the medications before we drive them. Keep in mind that drug companies come in business to generate income and that they would say everything to keep people on the medications.

Researchers found that participants using this drug for the year, dropped excess weight within one month and have kept the extra weight off during the entire 56 weeks in the study. Contrave is a combination with the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which can be made up of multiple active ingredient, which can make them more potent and safer.

Combo-pilling may be the newest fad or even better the newest in the future under scrutiny and so it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular may be the fact that by right now there are no long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures really are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug can also raise blood pressure level and heartbeat, and really should not be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise hypertension and pulse rate and must not be used in patients with uncontrolled high hypertension, as well as by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients using a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients on the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.

'The intent of the bill is to give police officers and district attorneys a power tool to address illicit drug use among women that are pregnant through treatment programs," Tennessee governor Bill Haslam said.